药物分析专业词汇题库.doc

药物分析专业词汇绪论释药系统（drug delivery system，DDS）中国药典（Chinese Pharmacopoeia,ChP）美国药典（The United States Pharmacopoeia,USP）美国国家处方集（The National Formulary,NF）英国药典（British Pharmacopoeia,BP）欧洲药典（European Pharmacopoeia,Ph.Eup）国际药典（The International Pharmacopoeia,Ph.Int）良好药品实验研究规范（Good Laboratory Practice,GLP）良好药品生产规范(Good Manufacture Practice,GMP)良好药品供应规范(Good Supply Practice,GSP)良好药品临床试验规范(Good Clinical Practice,GCP)分析质量管理(Analytical Quality Control,AQC)第1章 药物的鉴别试验药物的鉴别试验identification test一般鉴别试验general identification test专属鉴别试验specific identification test灵敏度sensitivity最低检出量minimum detectable quantity最低检出浓度minimum detectable concentration第2章 药物的杂质检查巯基醋酸mercaptoacetic acid古蔡Gutzeit二乙基二硫代氨基甲酸银siliver diethyldithio-carbamate硫酸灰分sulphated ash炽灼残渣residue on ignition热重分析法thermogravimetric analysis,TGA差示热分析法differential thermal analysis,DTA差示扫描量热法differential scanning calorimetry,DSC碱性酒石酸铜试验Fehlings reagent异红紫酸盐isopurpurate2，3-二氨基萘2,3-diaminonaphthalene4，5-苯并苯硒二唑4，5-benzopiazselenol第三章 定量分析样品前处理与测定方法的效能指标汞齐化法amalgamation method氧瓶燃烧法oxygen flask combustion method葡萄糖醛酸甙glucuronides硫酸酯sulphates血浆plasma血清serum全血whole blood治疗药物浓度监测therapeutic drug monitoring,TDM结合bound游离free缀合物conjugate液-液提取法liquid-liquid extraction,LLE离子对试剂ion pair reagent离子对提取法ion pair extraction method反离子counter液-固提取法liquid-solid extraction LSE半自动样品制备系统advanced automated sample processor,AASP烷基化alkylations酰基化acylations硅烷化silylations精密度precision标准差standard deviation,SD orS相对标准差relative standard deviation,RSD变异系数coefficient of variation,CV批内精密度within-run precision日内精密度within-day precision批间精密度between-run precision日间精密度day to day precision准确度accuracy定量限limit of quantitation,LOQ检测限limit of detection,LOD选择性selectivity专属性specificity线性与范围linearity and range重现性ruggedness耐用性robustness散布图scatter diagram荧光偏振免疫测定法fluorescence polarization immunoassay，FPIA第4章 巴比妥类药物的分析溴化十六烷基三甲基苄铵cetyltrimethylbenzylammonium bromide，CTMA氯化四癸基二甲基苄铵Tetradacyldimethybenzylammonium chloride，TDBA第5章 芳酸及其酯类药物的分析苯甲酸及其钠盐benzoic acid and sodium benzoate布美他尼bumetanide羟苯乙酯ethylparoben丙磺舒probenecid酚黄乙胺etamsylate第6章 胺类药物的分析第七章 杂环类药物的分析二硝基氯苯反应Vongerichten反应戊烯二醛反应K?nig反应第8章 生物碱类药物的分析生物碱alkaloids阿片gum opium扫尾剂tailing-suppressing reagent蒂巴因thebaine诺司卡品noscapine竞争离子competing ions亲脂性lipophicity拖尾因子tailing factor金刚烷adamantane第9章 维生素类药物的分析维生素vitamin去氢维生素A dehydroretinol去水维生素A anhydroretinol鲸醇kitol三氯化锑反应Carr-Price反应维生素B1 thiamine hydrochloride；盐酸硫胺2，3，5-三苯基氯化四氮唑 2，3，5-triphenyltetrazolium chlorid，TTC红四氮唑red tetrazoline，RT蓝四氮唑blue tetrazoline，BT3，3-二甲基氧苯基-双-4，4-（3，5-二苯基）氯化四氮唑3，3-dianisole-bis4，4-（3，5-dipheny）tetrazolium chloride有色甲 formazan铁-酚试剂iron-phenol reagent铁-柯柏试剂iron-Kober reagent第十一章 抗生素类药物的分析6-氨基青霉烷酸6-aminopenicillanic acid，6-APA7-氨基头孢菌烷酸7-aminocephalosporanic acid，7-ACA氨苄西林ampicillin5-甲基-3-邻氯苯基-4-异唑青霉素钠cloxacillin sodium羟氨苄青霉素amoxicillin氨基糖甙类抗生素aminoglycosides antibiotics链霉素streptomycin麦芽酚maltolN-甲基葡萄糖胺反应Elson-Morgan反应坂口反应 Sakaguchi反应庆大霉素gentamycin四环素类tetracyclines4-差向脱水四环素 4-ejpianhydrotetracycline，EATC第十二章 药物制剂分析含量均匀度content uniformity溶出度dissulution离子对高效液相色谱法ion-pair，HPLC第十三章 生化药物分析概论第十四章 中药制剂分析概论超临界流体萃取supercritical fluid extraction，SFE过弗罗里Florisil第十五章 药品质量标准的制定国际非专利药名International Names for Pharmaceutical Substances，INN去氧麻黄碱Metamfetaminum国际理论和应用化学联合会International Union of Pure and Applied Chemistry，IUPAC有机化学命名原则Nomenclature of Organic Chemistry可待因Codeinum地塞米松Dexamethasonum氯Chloroquinum青蒿素Artemisininum吗啡Morphinum苯扎溴铵Benzalkonii Bromidum1-（3，4-二羟苯基）-2-氨基乙醇重酒石酸盐一水合物1-（3，4-Dihydroxyphenyl）-2-Aminoethanol Bitartrate mono-hydrate第十六章 药品质量控制中的新方法与新技术填充柱packed column开管柱open tubular column空心柱capillary column熔融石英开管柱fused silica open tubular column，FSOT高分辨率气相色谱法high resolution gas chromatography，HRGC壁涂开管柱wall-coated open tubular column，WCOT柱固定化相开管柱immobilized phase open tubular column ，IPOT柱交联柱crosslinking column键合相柱bonding phase column不可提取相开管柱nonextractable phase open tubular column，NPOT柱多孔层开管柱porous-layer open tubular column，PLOT柱担体涂渍开管柱support-coated open tubular column，SCOT柱分流进样split injection不分流进样splitless injection柱头进样on-column injection直接进样direct injection手性分离色谱chiral separation chromatography，CSC普萘洛尔propranolol沙粒度胺thalidomide测定对映体enantiomer手性固定化chiralstationary phase，CSP手性衍生试剂chiral derivatization reagent，CDR非对映异构体diastereoisomer，DSTM配基交换型手性添加剂chiral ligand-exchange complexes，CLEC手性离子对络合剂chiralion pair complex，CIPC环糊精cyclodextrins，CD葡聚糖sephadex配基交换剂ligand exchanger手性传荷charge transfer（R）-N-3，5-二硝基苯甲酰苯基苷氨酸dimitrobenzyl phenylglycin；DNBPG三点手性识别模式three-point chiral recognition model噻吗洛尔thimolol曲洛磷胺trofosfamide乙酰葡萄糖异硫氰酸酯（2，3，4，6-tetra-O-acetyl-D-glucopyranosylisothiocyanate，GITC左旋比喹酮L-praziquantel比喹胺praziquanamine苯丙胺phenylpropamine异氰酸-萘酯（-naphthylisocyanae，NI美西律mexiletine氯胺酮ketamine本芴醇benflumelol苯丙醇phenyl propanol烯丙洛尔alprenolol普萘洛尔propranolol氧烯洛尔 oxyprenolol麻黄碱ephedrine毛细管电泳capillary electrophoresis，CE毛细管区带电泳capillary zone electrophoresis，CZE胶束动电毛细管色谱mcellar electrokinetic capillary chromatography，MECC胶束动电色谱miccellar electrokinetic chromatography，MEKC环糊精动电色谱cyclodextrins electrokinetic chromatography，CDEKC离子交换动电色谱ion-exchange electrokinetic chromatography，IEEKC微滴乳状液动电色谱microemulsion electrokinetic chromatography，MEEKC毛细管凝胶电泳capillary gel electrophoresis，CGE毛细管等电聚焦capillary isoelectric focusing，CIEF毛细管等速电泳capillary isotachorphoresis，CITP毛细管电色谱capillary electrochromatography ，CEC色谱响应函数chromatographic response function，CRF色谱优化函数chromatographic optimization function，COF等级色谱响应函数hierarchical chromatographic response function，HCRF差示分光光度法difference spectrophotometry近红外光谱near infra-red spectrum，NIRS中红外光谱mid infra-red spectrum，MIRS合谱combinations光谱匹配法spectral matching匹配指数match index，M.I.主成分分析法principal component regression，PCR人工神经网络方法artificial neural networks，ANN核磁共振nuclear magnetic resonance，NMR二维NMR two dimensional NMR六甲基三硅氧烷hexam ethylcyclotrisiloxane吡嗪pyrazine普鲁卡因procaine色谱联用技术hyphenated techniques chromatography，HTC接口interface重建色