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From Concept to Preliminary Results AMEE 2009 Malaga, Spain Pablo Pulido M, MD, President Alberto Oriol I Bosh, MD, Vice President Toward Leadership and Innovation in Professional Development To promote life long learning through continuing professional development among family physicians and general practitioners in mid and lower income countries by developing programs, standards, resources and partnerships that foster higher quality care for patients and communities Our MissionShift of Emphasis from Live long Learning to the Quality of Primary Health Care Services To increase the quality of health care in mid- and lower-income countries by engaging primary care physicians in robust continuing professional development and practice improvement programs designed to meet country specific public health priorities 2005 2009 2005 Origination of the idea, reality testing Approximately 80 % of these deaths are in emerging countries; Economic burden on the health systems Availability of surrogate measures Educational Intervention 2004 2030 Disease or Injury Deaths Rank Rank Deaths Disease or injury (%) (%) Ischaemic heart disease 12.2 1 1 14.2 Ischaemic heart disease Cerebrovascular disease 9.7 2 2 12.1 Cerebrovascular disease Lower respiratory infections 7.0 3 3 8.6 Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease 5.1 4 4 3.8 Lower respiratory infections Diarrheal diseases 3.6 5 5 3.6 Road traffic accidents HIV/AIDS 3.5 6 6 3.4 Trachea, bronchus, lung cancers Tuberculosis 2.5 7 7 3.3 Diabetes mellitus Trachea, bronchus, lung cancers 2.3 8 8 2.1 Hypertensive heart disease Road traffic accidents 2.2 9 9 1.9 Stomach cancer Prematurity and low birth weight 2.0 10 10 1.8 HIV/AIDS Neonatal infections and other* 1.9 11 11 1.6 Nephritis and nephrosis Diabetes mellitus 1.9 12 12 1.5 Self-inflicted injuries Malaria 1.7 13 13 1.4 Liver cancer Hypertensive heart disease 1.7 14 14 1.4 Colon and rectum cancers Birth asphyxia and birth trauma 1.5 15 15 1.3 Oesophagus cancer Self-inflicted injuries 1.4 16 16 1.2 Violence Stomach cancer 1.4 17 17 1.2 Alzheimer and other dementias Cirrhosis of the liver 1.3 18 18 1.2 Cirrhosis of the liver Nephritis and nephrosis 1.3 19 19 1.1 Breast cancer Colon and rectum cancers 1.1 20 20 1.0 Tuberculosis Violence 1.0 22 21 1.0 Neonatal infections and other* Breast cancer 0.9 23 22 0.9 Prematurity and low birth weight Oesophagus cancer 0.9 24 23 0.9 Diarrheal diseases Alzheimer and other dementias 0.8 25 29 0.7 Birth asphyxia and birth trauma 41 0.4 Malaria * Comprises severe neonatal infections and other, noninfectious causes arising in the perinatal period. about the same large increase large decrease Projected Leading Causes of Death 2030 Blended learning approach: Standard tool: Online self directed learning activity Reinforcement tools: facilitated face-to-face discussions, self assessment exercises, online discussion board, reminders Enabling tools: reference lists, best practice guidelines, patient education materials and tools Alternating Methods: In-country orientation, online didactic, in-country clinic, online didactice etc. etc. Focus on Practice Improvement: Physicians assess CV risk level of cohort of patients Physicians establish treatment goals In-country sessions aimed at practice improvement planning and problem solving Data on patient progress provided to physicians Pilot course design Inclusion Criteria Primary Care Physicians Hospitals/ Private Practices Attending 100 patients with CV RF/month Practicing in the Project GLOBE pilot country Internet Connection Access to computer Working knowledge of English Consenting to the protocol Study participants Exclusion Medical Students Non Primary Care PCPs not interested in participation % of Patients with controlled Cholesterol level ( goal 200 mg/dL 6.2 mMol/L % of Patients with controlled hypertension ( goal 140/90 mm Hg) Primary endpoints: Bio Markers of CV health care Physicians knowledge (tests) Physicians satisfaction (tests, interviews) Attitudes (interviews) Additional secondary endpoints % of Patients with smoking behavior % of Diabetic patients with controlled blood glucose ( 110 mg/dL) Mean BMI (lean, 25; overweight, 25-29; and obese, 30) or weight in the total patient population / waist circunference Changes in Risk Factor Score (Framingham) Secondary enpoints: Traditional Metrics Week Evaluation Frequency Baseline Physician Knowledge, skill and satisfaction Biomarkers metrics Informed consent qd 112 intervention Web based lesson and web cast Live workshops Offline study reading Patient Education Weekly Fortnightly As appropriate Daily (at the clinic) 1352 specifically on weeks 28, 40 and 52 Biomarkers markers Knowledge, skills and satisfaction Patient education at indicated weeks Daily (at the clinic) Evaluation Sponsors Li Ka Shing Knowledge Institute at The University of Toronto Support, Partners and Participating Countries Participating Countries: Colombia Russia Turkey Venezuela Partners: * *Exploratory Relationship o Project Timeline Felix Vartanyan, MD Project Globe in the Russian Federation Administrative Structure of Project Globe in Moscow Ministry of Heath and Social Development Russian Academy of Advanced Medical Studies Polyclinic No 97 Polyclinic No 81 Polyclinic No 146 Polyclinic No 151 Comprehensive Training Program Improvement of training quality of primary health care staff for prevention and treatment of cardiovascular pathology Main Components of Comprehensive Training Program Selected issues of management From obesity to metabolic syndrome Ischemic Heart Disease Tactic of management of patients with hypertension School for outpatients of district polyclinics To promote continuing professional development and PHC physicians “Hypertension Prevention” Formation Process of Competention Effective Training Programs Biomedical Advances Training Technologie s Educational Programs Development Improvement of Health Quality Educational Intervention Model of Project Globe Development e-learning 11 modules CD/DVD, Internet, Training Physicians Patient Education Clinical Observations Efficacy of Educational Intervention Moscow Polyclinics Involved in Project Globe Study* Polyclinic No Involved Expected No Physicians Patients Patients 97 9 100 270 81 15 212 300 146 12 196 260 151 11 100 300 Total: 47 608 1130 *Time of observation: 1 year Tripartite System Educational Program District Physician Patient Training Program Teacher District Physician Interaction Between Training and Practice Training Effectiveness Improvement of health indicators HEALTH Outcomes Population Data Entry Forms Demographic Breakdown Age Distribution (n =574) Age Group #Subjects 450 124 Gender Female Male Hypertension mm Hg Normal 25 Pre 83 Grade 1 286 Grade 2 180 Cholesterol mg/dL 200 154 200-220 110 220-300 127 300-400 69 400+ 114 Risk Factors: Preliminary Results* % Change from Initial Visit to 3 Months n=574 Parameter Baseline 3 mos. D % change* Total Cholesterol (mg/dl) 270.9 264.5 -6.4 -2.4% LDL (mg/dl) 176.5 171.2 -5.3 -3.0% Systolic (mmHg) 146.7 141.6 -5.1 -3.5% Diastolic (mmHg) 88.1 84.2 -3.9 -4.4% Triglycerides (mg/dl) 240.0 234.0 -6.0 -2.5% Plasma Glucose (mg/dl) 99.9 96.3 -3.6 -3.6% Weight (kg) 80.9 79.5 -1.4 -1.7% Waistline (cm) 89.5 88.3 -1.2 -1.3% Cigarettes (per day) 6.3 4.8 -1.5 -23.8% Exercise hours (per week) 2.6 3.2 0.6 +23.1% *p0.05 Preliminary Results by Gender* % Change from Initial Visit to 3 Months n=574 Measure Female Male Total Cholesterol (mg/dl) -2.4% -2.4% LDL (mg/dl) -2.9% -3.4% Systolic (mmHg) -3.3% -4.0% Diastolic (mmHg) -4.5% -4.0% Triglycerides (mg/dl) -2.4% -3.4% Plasma Glucose (mg/dl) -3.2% -5.2% Weight (kg) -1.6% -2.4% Waistline (cm) -1.3% -1.9% Cigarettes (per day) -24.1% -24.4% Exercise hours (per week) 25.5% 26.3% 450 124 *p0.05 Preliminary Results for Hypertension by Grade* % Change from Initial Visit to 3 Months n=549 Pre Hypertension Hypertension Measure Hypertension Grade 1 Grade 2 Total Cholesterol (mg/dl) -2.2% -2.6% -2.0% LDL (mg/dl) -6.1% -2.5% -1.9% Systolic (mmHg) -2.1% -2.9% -5.6% Diastolic (mmHg) -4.5% -4.1% -5.7% Triglycerides (mg/dl) -0.3% -2.3% -3.2% Plasma Glucose (mg/dl) -4.4% -3.7% -3.9% Weight (kg) -0.9% -1.8% -2.3% Waistline (cm) -0.8% -1.4% -1.8% Cigarettes (per day) -20.8% -24.4% -26.2% Exercise hours (per week) 19.9% 26.8% 32.3% 83 286 180 *p0.05 Preliminary Results for High Total Cholesterol subjects* % Change from Initial Visit to 3 Months n=420 TOTAL Measure 200+ 200-220 220-300 300-400 400+ n 420 110 127 69 114 Total Cholesterol (mg/dl) -2.6% -0.9% -2.3% -3.8% -3.1% LDL (mg/dl) -3.4% -1.4% -1.6% -5.6% -4.8% Systolic (mmHg) -3.1% -3.9% -3.7% -2.4% -1.8% Diastolic (mmHg) -4.4% -4.7% -3.9% -6.3% -3.7% Triglycerides (mg/dl) -3.7% -3.7% -2.9% -2.0% - 2.4% Plasma Glucose (mg/dl) -3.6% -3.5% -4.6% -3.8% -3.0% Weight (kg) -1.3% -1.5% -1.9% -1.1% -0.4% Waistline (cm) -1.1% -1.3% -1.5% -0.7% -0.3% Cigarettes (per day) -23.9% -27.8% -28.7% -18.8% -19.2% Exercise hours (per week) -24.4% 34.3% 31.1% 17.9% 20.3% *p0.05 Project Globe Venezuela Ada Vedilei, MD Development of Project Globe Venezuela Building Pilot Relationships between PGC and local leaders Venezuelan Coordinating Team established with local leaders Identifying Needs & Priority Diseases Systems Level Organizational Level Individual Level Existing Data Interviews Online Questionnaires Data Sources Focus Group Pilot Studies Proof of Concept Selection of Ambulatories Selection of Patients Selection of Physicians Data Management Training Computation Training Pilot Studies Proof of Concept Course Design FSFB Meeting Humana Group Teachers Meeting Making Videos Pilot Studies - Proof of Concept Pilot Studies Proof of Concept Course Design IM-Cardio: Blended Learning Problem Based Learning (PBL) Online Unit I Introduction & Generalities Unit II Therapeutic Management Unit III Therapeutic Education Workshop face to face Behavior Change Pilot Studies Proof of Concept Course Implementation Behavior Change Workshops Objetivos Justificacin Descripcin Introduccin a la Metodologa Sobre este Curso Mi curso Manual del Usuario 1. Generalidades 2. Manejo Teraputico 3. Educacin del Paciente Objetivos Justificacin Descripcin Introduccin a la Metodologa Sobre este Curso Mi curso 1. Generalidades 2. Manejo Teraputico 3. Educacin del Paciente Caso 1 2. MANEJO TERAPUTICO a. Nombre los FRCV que tiene este paciente: 01 02 03 04 05 06 07 08 Objetivos Justificacin Descripcin Introduccin a la Metodologa Sobre este Curso Mi curso Manual del Usuario 1. Generalidades 2. Manejo Teraputico 3. Educacin del Paciente Objetivos Justificacin Descripcin Introduccin a la Metodologa Sobre este Curso Mi curso 1. Generalidades 2. Manejo Teraputico 3. Educacin del Paciente Caso 1 Muy bien! Lo invitamos a continuar Aceptar 2. MANEJO TERAPUTICO Problemas sicolgicos (depresin) Impedimentos cognitivos Tratamiento de condiciones asintomticas Seguimiento inadecuado Reacciones adversas Falta de confianza en el tratamiento Incomprensin de la enfermedad Mala relacin mdico-paciente Barreras al cuidado o la medicacin Consultas fallidas Complejidad del tratamiento Mltiples medicaciones Fumadores Costos c. Detecte tres predictores de baja adhesion en este paciente Tratamiento de condiciones asintomticas Seguimiento inadecuado Fumadores Data Review and Impact - Demographic Breakdown n=245 Age DistributionAge Group # Subjects Gender Female 173 Male 71 Hypertension Normal 11 Pre 61 Grade 1 114 Grade 2 59 Cholesterol Range 200 80 200-220 45 220-240 41 240-260 39 0 50 100 150 30 30-34 35-39 40-44 45-49 50-54 55-59 60+ 6 6 9 18 25 38 49 89 260+ 40 Risk Factors: Preliminary Results % Change from Initial Visit to 3 Months n=245 Parameter Baseline 3 mos. D % change* Total Cholesterol (mg/dl) 218.7 198.9 -19.8 -9.1% LDL 137.0 122.2 -14.8 -10.8% HDL 45.0 46.9 1.9 +4.1% Systolic (mmHg) 142.7 137.6 -5.1 -3.6% Diastolic (mmHg) 87.8 80.7 -7.1 -8.1% Triglycerides (mg/dl) 182.9 163.1 -19.7 -10.8% Plasma Glucose (mg/dl) 104.4 105.2 0.8 0.7% BMI 30.0 28.9 -1.1 -0.4% *p0.05 Preliminary Results by Gender % Change from Initial Visit to 3 Months n=245 Measure Female Male Total Cholesterol (mg/dl) -6.5% -11.3% LDL (mg/dl) -10.4% -12.2% HDL (mg/dl) +1.5% +10.5% Systolic (mmHg) -2.8% -5.0% Diastolic (mmHg) -8.9% -6.0% Triglycerides (mg/dl) 4.9% 3.4% Plasma Glucose (mg/dl) -12.1% -27.6% BMI -0.1% -1.0% *p0.05 173 71 Preliminary Results for Hypertension by Grade % Change from Initial Visit to 3 Months n=245 Pre Hypertension Hypertension Measure Hypertension Grade 1 Grade 2 Total Cholesterol (mg/dl) -7.8% -5.8% -7.4% LDL (mg/dl) -7.6% -8.7% -16.2% HDL (mg/dl) +6.1% +0.7% +10.5% Systolic (mmHg) -0.1% 0.5% -12.0% Diast

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